University of Connecticut-Wesleyan University Stem Cell Core
Established in 2006, the University of Connecticut (UConn)-Wesleyan University Stem Cell Core is currently located in the Cell and Genome Sciences (CGS) Building, UConn Health at 400 Farmington Avenue, Farmington, Connecticut. Since its establishment, the Core has substantially contributed to the Connecticut stem cell initiative by providing a central source of technologies and materials for research on human embryonic stem cells (hESC) and induced pluripotent stem cells (iPSC).
Initially supported with institutional funds from UConn, and subsequently by the Connecticut State Stem Cell Research Program, we have expanded to incorporate a Genetics and Genomics Division located on the Storrs campus and provide a wide range of services. We have also incorporated a Genome Editing Division by collaborating with the Gene Targeting and Transgenics Facility at UConn Health.
With these crucial services, many UConn researchers have developed novel approaches to addressing fundamental biological questions and tackling deleterious diseases, and produced significant progress. Competitive state stem cell funding has been awarded to many UConn and Wesleyan researchers since 2006.
- Distribution of hESC/iPSC lines
- Genome integrity analysis
- Genome editing based on TALENs
- Training for hESC/iPSC culture, and workshops on cutting-edge technologies
- Derivation of hiPSC lines
- Quality control services and reagents
- Outreach educational programs